Oral Immunization of FMDV Vaccine Using pH-Sensitive and Mucoadhesive Thiolated Cellulose Acetate Phthalate Microparticles
نویسندگان
چکیده
منابع مشابه
Water dispersible microbicidal cellulose acetate phthalate film
BACKGROUND Cellulose acetate phthalate (CAP) has been used for several decades in the pharmaceutical industry for enteric film coating of oral tablets and capsules. Micronized CAP, available commercially as "Aquateric" and containing additional ingredients required for micronization, used for tablet coating from water dispersions, was shown to adsorb and inactivate the human immunodeficiency vi...
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DNA vaccines are usually given by intramuscular injection or by gene gun delivery of DNA-coated particles into the epidermis. Induction of mucosal immunity by targeting DNA vaccines to mucosal surfaces may offer advantages, and an oral vaccine could be effective for controlling infections of the gut mucosa. In a murine model, we obtained protective immune responses after oral immunization with ...
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ژورنال
عنوان ژورنال: Tissue Engineering and Regenerative Medicine
سال: 2017
ISSN: 1738-2696,2212-5469
DOI: 10.1007/s13770-017-0082-x